Recognizing the Patients Phenotype through Systems Biology

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data

The Human Phenotype Ontology (HPO) project, available at http://www.human-phenotype-ontology.org, provides a structured, comprehensive and well-defined set of 10,088 classes (terms) describing human phenotypic abnormalities and 13,326 subclass relations between the HPO classes. In addition we have developed logical definitions for 46% of all HPO classes using terms from ontologies for anatomy, ...

Recognizing Student Misconceptions through Ed's Tools and the Biology Concept Inventory

Integrating Biology and Climate Through Systems Science

The genomic and postgenomic eras have provided unprecedented potential to understand plants’, microbes’, and even entire communities’ molecular and cellular responses to global change. Early efforts to apply genomic technologies and concepts to climate change research are already improving our capability to predict organism response to such change. For example, genome-wide analyses of soybean a...

Systems biology and the biology of systems.

When I sit down to write an editorial for Physiology, I flatter myself that the two or three people who will ultimately read it want to hear my thoughts on a “big” topic. It strikes me that, within the rarefied realm of academic biology, there few bigger topics, or at least few topics more all encompassing in their scope, than Systems Biology. Perhaps it is the ambiguity inherent in its name th...

Recognizing Text Through Sound Alone

This paper presents an acoustic sound recognizer to recognize what people are writing on a table or wall by utilizing the sound signal information generated from a key, pen, or fingernail moving along a textured surface. Sketching provides a natural modality to interact with text, and sound is an effective modality for distinguishing text. However, limited research has been conducted in this ar...